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Title 

Two tetranucleotide repeats within the Xq21.3/Yp11.2 human specific region of homology and their conservation in primate evolution

Authors 

Heui Soo KimC WinstanleyR V WadekarO TakenakaF MitsunagaT KageyamaByung Hwa HyunT J Crow

Issue Date 

1999

Citation 

Zoological Science, vol. 16, no. 0, pp. 357-362

Abstract 

We locate two tetranucleotide repeat sequences (AT3 and T2C2) between the markers sY44 and sY46 within the Xq21.3/Yp block of homology that has been created since the separation of the chimpanzee and human lineages, and trace their origin in primate evolution. The T2C2 repeat is present only in hominoid primates. The sequence AT3 is present in Old World monkeys but not in New World monkeys, and has been lost in some gibbon species. In the bonobo, the AT3 repeat is the site of a new Alu insertion. These findings and their relationship to the conservation of other markers in this region cast light on the structure of a genomic region that has been subject to change in the course of primate evolution and may include one or more sites of instability.

ISSN 

0289-0003

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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