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Title 

An antioxidant lignan and other constituents from the root bark of Hibiscus syriacus

Authors 

Sang Jun LeeYoung Sook YunIn Kyoung LeeIn Ja RyooBong Sik YunIck Dong Yoo

Publisher 

Georg Thieme Verlag

Issue Date 

1999

Citation 

Planta Medica, vol. 65, no. 0, pp. 658-660

Keywords 

antioxidantlignananimal cellcarbon nuclear magnetic resonancemedicinal plantnonhumanplant rootproton nuclear magnetic resonancestructure analysisanimals

Abstract 

A new lignan named as hibiscuside, (+)-pinoresinol 4-O-[β- glucopyranosyl (1→2)-α-rhamnoside] (1), and a known lignan, syringaresinol (2) were isolated from the root bark of Hibiscus syriacus together with two feruloyltyramines (3,4) and three known isoflavonoids (5, 6,7). The structures of these compounds have been established on the basis of their NMR, mass, UV spectra. Among these phenolic compounds, 6-O-acetyldaidzin (5), 6-O-acetylgenistin (6), and 3'-hydroxydaidzein (7) with IC50 values of 8.2, 10.6, and 4.1 μM, respectively, significantly inhibited lipid peroxidation in rat liver microsomes. Hibiscuside (1), E- and Z-N-feruloyl tyramines (3,4) exhibited moderate antioxidant activity.

ISSN 

0032-0943

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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