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Title 

A Novel HLA-DR12 Allele (DRB1*1206) Found in a Korean B-Cell Line

Authors 

C Y MaengK H KimJ H KangH HanKil Lyong Kim

Publisher 

Wiley-Blackwell

Issue Date 

1999

Citation 

Tissue Antigens, vol. 53, no. 0, pp. 516-518

Keywords 

HLA-DRB1*1206cDNA cloningKorean B-cell lineasymmetric PCR-SSCP

Abstract 

At least 6 HLA-DRB1*12 alleles have been identified to date with nucleotide polymorphism occurring at codons 37, 57-58, 60, 67, 85 and 87. In this report, we describe the identification of another new HLA-DRB1*12 allele: DRB1*1206. This novel allele was found in an Epstein-Barr virus (EBV)-transformed Korean B-cell line 'K-KT' having the HLA-phenotype A3, 24; B44, 61; Cw3; Bw4, 6; DR12, 13 during full-length cDNA isolation for cell line characterization and for production of HLA-DR recombinant proteins. The allele was identified initially by cycle sequencing of subcloned HLA-DRB full-length cDNA.

ISSN 

0001-2815

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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