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Title 

Inhibitory constituents against HIV-1 protease from Agastache rugosa

Authors 

Byung Sun MinMasao HattoriHyeong Kyu LeeYoung Ho Kim

Publisher 

Pharmaceutical Society of Korea

Issue Date 

1999

Citation 

Archives of Pharmacal Research, vol. 22, no. 1, pp. 75-77

Keywords 

Agastache rugosaLabiataeAgastanolAgastaquinoneAnti-HIV-1 protease activity

Abstract 

Two diterpenoid compounds, agastanol (1) and agastaquinone (2), were isolated from the roots of Agastache rugosa (Labiatae). Compound 1 and 2 showed significant inhibitory effects against human immunodeficiency virus type 1 (HIV-1) protease activity with IC50 values of 360 and 87 μm, respectively.

ISSN 

0253-6269

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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