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Title 

Optimal pH control of batch processes for production of curdlan by Agrobacterium species

Authors 

Jung Heon LeeIn Young LeeMi Kyoung KimYoung Hoon Park

Publisher 

Springer

Issue Date 

1999

Citation 

Journal of Industrial Microbiology (& Biotechnology), vol. 23, no. 0, pp. 143-148

Keywords 

curdlan productionoptimal pH profilebatch process

Abstract 

We sought an optimal pH profile to maximize curdlan production in a batch fermentation of Agrobacterium species. The optimal pH profile was calculated using a gradient iteration algorithm based on the minimum principle of Pontryagin. The model equations describing cell growth and curdlan production were developed as functions of pH, sucrose concentration, and ammonium concentration, since the specific rates of cell growth and curdlan production were highly influenced by those parameters. The pH profile provided the strategy to shift the culture pH from the optimal growth condition (pH 7.0) to the optimal production one (pH 5.5) at the time of ammonium exhaustion. By applying the optimal pH profile in the batch process, we obtained significant improvement in curdlan production (64 g L-1) compared to that of constant pH operation (36 g L-1).

ISSN 

0169-4146

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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