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Title 

Isolation of p-hydroxycinnamaldehyde as an antibacterial substance from the saw fly, Acantholyda parki S.

Authors 

Jae Yoon LeemIm Ju JeongKyu Tek ParkHo Yong Park

Publisher 

Elsevier

Issue Date 

1999

Citation 

FEBS Letters, vol. 442, no. 0, pp. 53-56

Keywords 

Insect immunityp-HydroxycinnamaldehydeAntibacterial substanceAntifungal activityInsect defense moleculeAcantholyda parki S.

Abstract 

We purified an antibacterial substance from larvae of the saw fly, Acantholyda parki S., and identified its molecular structure as p-hydroxycinnamaldehyde. We then synthesized it by reduction of p-hydroxycinnamic acid. The antibacterial activity of the synthetic p-hydroxycinnamaldehyde was equal to that of the authentic substance. This molecule was found to have a broad antibacterial spectrum against not only Gram-negative, but also Gram-positive bacteria. Furthermore, it showed antifungal activity against Candida albicans. We suggest that this substance may play a role in the defense system of this insect. This is the first report of p-hydroxycinnamaldehyde of animal origin.

ISSN 

0014-5793

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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