상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Isolation of cDNA clones encoding human histone macroH2A1 subtypes

Authors 

Yong Hee LeeMi Hui HongJae Wha KimYun Mi HongYong Kyung ChoeSung Yeoul ChangKwang Soo LeeIn Seong Choe

Publisher 

Elsevier

Issue Date 

1998

Citation 

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1399, no. 1, pp. 73-77

Keywords 

macroH2A1 subtypecDNA sequencetissue distribution(Human)

Abstract 

cDNA clones encoding two different subtypes of histone macroH2A1, macroH2A1.1 and macroH2A1.2, have been isolated from human liver tissue. The open reading frames in the isolated clones predicted proteins comprising 368 and 371 amino acids respectively. Estimated molecular masses of the two proteins were 39.0 kDa and 39.4 kDa. Human histone macroH2A1.1 and macroH2A1.2 showed about 98% identity with their counterparts isolated from rat. The features of the nucleotide sequences of the two macroH2A1 subtypes in human were the same as in the rat system. Northern blot analysis showed that the macroH2A1.1 and macroH2A1.2 subtypes were expressed as mRNA species with a size of 1.5 and 4.4 kb, respectively. They were expressed in all human tissues examined.

ISSN 

0167-4781

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)