상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Three naphthalenes from root bark of Hibiscus syriacus

Authors 

Ick Dong YooBong Sik YunIn Kyung LeeIn Ja RyooDong Ho ChoungKyou Hoon Han

Publisher 

Elsevier

Issue Date 

1998

Citation 

Phytochemistry, vol. 47, no. 5, pp. 799-802

Keywords 

hibiscus syriacusmalvaceaeroot barksyriacusinsnaphthalenecarbolactonelipid peroxidation inhibitory activitycytotoxicity

Abstract 

Three new naphthalenes, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. These compounds were identified as 2,7-dihydroxy-6-methyl-8-methoxy-l-naphthalenecarbaldehyde, 2-hydroxy-6- hydroxymethyl-7,8-dimethoxy-l-naphthalenecarbaldehyde, 1-carboxy-2,8- dihydroxy-6-methyl-7-methoxynaphthalenecarbolactone (1 → 8), respectively, on the basis of various spectral studies. The compounds inhibited lipid peroxidation with IC50s of 0.54,5.90 and 1.02 μg ml-1, respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 μg ml-1.

ISSN 

0031-9422

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)