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Title 

Effects of medium components on L-ornithine production by Brevibacterium ketoglutamicum

Authors 

Tae Ho LeeYong Keun ChangWook Sang RyuBong Hyun ChungYoung Hoon Park

Publisher 

Springer Verlag (Germany)

Issue Date 

1996

Citation 

Biotechnology and Bioprocess Engineering, vol. 1, no. 1, pp. 41-45

Keywords 

auxotrophbrevibacterium ketoglutamicumL-arginineL-ornithine

Abstract 

Effects of yeast extract and ammonium sulfate were investigated on the production of L-ornithine by an arginine auxotroph, Brevibacterium ketoglutamicum in flask and batch cultures. Yeast extract as an arginine source and ammonium sulfate as an inorganic nitrogen source had significant effects on L-ornithine production and cell growth. L-ornithine production was repressed by the excessive addition of arginine Reversion of auxotrophic cells to the wild type was observed when the initial yeast extract concentration was too low. There existed optimum concentrations of yeast extract and ammonium sulfate for L-ornithine production. The effects of yeast extract and ammonium sulfate concentrations on the Leudeking-Piret model parameters were examined to analyze the relationship between cell growth and L-ornithine production.

ISSN 

1226-8372

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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