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Title 

A Tetrodotoxin-Producing Vibrio Strain, LM-1, from the Puffer Fish Fugu vermicularis radiatus

Authors 

Myoung Ja LeeDong Youn JeongWoo Seong KimHyun Dae KimCheorl Ho KimWon Whan ParkYong Ha ParkKyung Sam KimHyung Min KimDong Soo Kim

Publisher 

American Society for Microbiology

Issue Date 

2000

Citation 

Applied and Environmental Microbiology, vol. 66, no. 4, pp. 1698-1701

Keywords 

tetrodotoxinanimal cellbacterium isolationfish diseasegas chromatographyhigh performance liquid chromatographymass spectrometrynonhumanstrain differencethin layer chromatography

Abstract 

Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

ISSN 

0099-2240

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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