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Title 

Coumarins from the roots of Angelica decursiva-albiflora

 

개바디 뿌리의 쿠마린성분

Authors 

Nam Il JungChang Soo YookHyeong Kyu Lee

Publisher 

Korean Society of Pharmacognosy

Issue Date 

1994

Citation 

Korean Journal of Pharmacognosy, vol. 25, no. 4, pp. 311-318

Keywords 

angelica decursiva-albifloracoumarinpyranocoumarinfuranocoumarindecursinumbelliferonenodakenetinnodakenindecuroside Ⅰcytotoxicity

Abstract 

From the root of Angelica decursiva-albiflora Yook, which has been used as a folk medicine for a sedative, analgesic and expectorant, four free coumarins, e.g., decursidin(I), decursin(II), umbelliferone (III) and nodakenetin (IV), and two coumarin glycosides, e.g., nodakenin (V) and decuroside I(VI) were isolated. The cytotoxicity of nodakenin(V) against L-1210 leukemia cells was less effective than cisplatin, but in the nephrotoxicity against rabbit kidney proximal tubular cell nodakenin(V) showed remarkably less nephrotoxicant than cisplatin.

ISSN 

0253-3073

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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