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Title 

Two new constituents of isodon excisus and their evaluation in an apoptosis inhibition assay

Authors 

Choong Hwan LeeJin Hee KimHo Jae LeeSang Myung LeeYung Hee Kho

Publisher 

American Chemical Society

Issue Date 

2001

Citation 

Journal of Natural Products, vol. 64, no. 5, pp. 659-660

Keywords 

apoptosis inhibitorIsodon excisus extractapoptosisIsodon excisus

Abstract 

Investigation of the whole plant of Isodon excisus resulted in the isolation of two new apoptosis inhibitors (1 and 2). Compounds 1 and 2 inhibited etoposide-induced apoptosis in U937 cells with IC50 values of 10.2 and 52.4 μg/mL, respectively. The structures of 1 and 2 were determined by spectral data interpretation.

ISSN 

0163-3864

Link 

http://dx.doi.org/10.1021/np000604g

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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