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Title 

Coumarins with monoamine oxidase Inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

Authors 

Bong Sik YunIn Kyoung LeeIn Ja RyooIck Dong Yoo

Publisher 

American Chemical Society

Issue Date 

2001

Citation 

Journal of Natural Products, vol. 64, no. 9, pp. 1238-1240

Keywords 

coumarin derivativehibiscus syriacus extractmonoamine oxidase inhibitorantioxidant activitydrug activitystructure activity relationcoumarinsinhibitory concentration 50lignansmonoamine oxidase inhibitors

Abstract 

A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC50 values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.

ISSN 

0163-3864

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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