상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Negative regulation of filamentous growth and flocculation by Lkh1, a fission yeast LAMMER Kinase homolog

Authors 

Kun Hoe KimYoung Mi ChoWon Hwa KangJi Hoon KimKwan Ho ByunYoon Dong ParkKyung Sook BaeHee Moon Park

Publisher 

Elsevier

Issue Date 

2001

Citation 

Biochemical and Biophysical Research Communications, vol. 289, no. 5, pp. 1237-1242

Keywords 

filamentous adhesionflocculationKns1LAMMER kinaseLkh1S. cerevisiaeS. pombeamino acidcomplementary DNAdivalent cation

Abstract 

We have isolated a full-length cDNA clone that encodes for a Schizosaccharomyces pombe homolog of the dual-specificity protein kinase of the LAMMER family, lkh1 (lammer kinase homolog). The proposed Lkh1 protein contains 575 amino acids. The lkh1+ null mutant is viable, but exhibits flocculation upon reaching stationary phase in liquid media and filamentous adhesion growth on solid media. Analysis of the flocculation activity of the lkh1+ null mutant indicates that asexual aggregation of S. pombe cells into floccules is divalent cation-dependent and galactose-specific. We also demonstrate that the Saccharomyces cerevisiae LAMMER kinase homolog, Kns1, can substitute for the Lkh1 function in S. pombe.

ISSN 

0006-291X

Link 

http://dx.doi.org/10.1006/bbrc.2001.6128

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)