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Title 

Inhibitory activity of lignan components from the flower buds of Magnoliae fargesii on the expression of cell adhesion molecules

Authors 

Kyung Seop AhnKeun Young JungJung Hee KimSei Ryang OhHyeong Kyu Lee

Publisher 

Pharmaceutical Society of Japan

Issue Date 

2001

Citation 

Biological & Pharmaceutical Bulletin, vol. 24, no. 9, pp. 1085-1087

Keywords 

Intercellular adhesion molecule-1lignanmagnoliae fargesiivascular cell adhesion molecule-1cell adhesion moleculeintercellular adhesion molecule 1vascular cell adhesion molecule 1cell linecell surfacedrug activity

Abstract 

Inhibitory activity of lignans isolated from Magnoliae fargesii Cheng on cell adhesion molecules on the surface of THP-1 human monocytic cell lines were investigated. Among 16 lignan components tested, six displayed relatively potent inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1).

ISSN 

0918-6158

Link 

http://dx.doi.org/10.1248/bpb.24.1085

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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