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Title 

Low-density lipoprotein-antioxidant constituents of Saururus chinensis

Authors 

Byung Tae AhnSang Ku LeeSae Bom LeeEun Sook LeeJae Gil KimSong Hae BokTae Sook Jeong

Publisher 

American Chemical Society

Issue Date 

2001

Citation 

Journal of Natural Products, vol. 64, no. 12, pp. 1562-1564

Keywords 

low density lipoproteinantioxidant activityantioxidantslipoproteins, LDLsaururus chinensis

Abstract 

A new diarylbutane lignan, saururin A (1), and a known 8-O-4′-type neolignan, machilin D (2), were isolated from a total methanol extract of the underground parts of Saururus chinensis. The structures of 1 and 2 were elucidated by spectroscopic data analysis. Compounds 1, 2, and virolin (3) (the methyl ether of 2) exhibited significant low-density lipoprotein (LDL)-antioxidant activity in the thiobarbituric acid-reactive substance (TBARS) assay with IC50 values of 8.5, 2.9, and 4.3 μM, respectively.

ISSN 

0163-3864

Link 

http://dx.doi.org/10.1021/np0006061

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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