상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

The expression of bok is regulated by serum in HC11 mammary epithelial cells

Authors 

Seok Ho HaSul Ra LeeTae Hoon LeeYoung Min KimMyung Gi BaikYun Jaie Choi

Publisher 

Springer Verlag (Germany)

Issue Date 

2001

Citation 

Molecules and Cells, vol. 12, no. 3, pp. 368-371

Keywords 

biosynthesiscell cultureepithelium cellgene expression regulationcells, culturedculture media, serum-freeepithelial cellsmammary glands, animal

Abstract 

Epithelial cells within the mammary gland undergo apoptosis during weaning. To determine the expression of Bok mRNA (a member of the pro-apoptotic Bcl-2 family) in the mammary gland and its regulation, we examined the expression of the Bok transcript in the mouse mammary gland and HC11 mammary epithelial cells in culture through RT-PCR. The Bok mRNA expression was found in the mammary gland. The expression of the Bok mRNA level was induced through serum starvation and overexpression of Bok induced apoptosis in HC11 cells in culture. These results indicate that the expression of Bok mRNA in the mammary gland is regulated through serum starvation. It also may be related to the mammary involution.

ISSN 

1016-8478

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)