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Title | Development of tripeptidyl farnesyltransferase inhibitors |
Authors | Hee Yoon Lee; Jeong Hun Sohn; Byoung-Mog Kwon |
Publisher | Elsevier |
Issue Date | 2002 |
Citation | Bioorganic & Medicinal Chemistry Letters, vol. 12, no. 12, pp. 1599-1602 |
Keywords | protein farnesyltransferase inhibitor; enzyme inhibitor; enzyme Inhibitors |
Abstract | The first example of tripeptide inhibitors of farnesyltransferase with sub-micromolar inhibition activity was developed based on the fact that CVFM is not a substrate for farnesyltransferase. |
ISSN | 0960-894X |
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Registered Date |
2017-04-19 |
