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Title 

Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor γ

Authors 

Bang Yeon HwangJeong Hyung LeeJeong Bum NamHang Sub KimYoung Soo HongJung Joon Lee

Publisher 

American Chemical Society

Issue Date 

2002

Citation 

Journal of Natural Products, vol. 65, no. 4, pp. 616-617

Keywords 

peroxisome proliferator activated receptor gammasaururus chinensis extractdrug effectreceptor upregulationsaururus chinensisreceptors, cytoplasmic and nuclearsaururus

Abstract 

Two new acyclic furanoditerpene compounds, saurufuran A (1) and B (2), were obtained from the root of Saururus chinensis, and their structures were elucidated by means of 1D and 2D NMR spectroscopic analyses. Saurufuran A (1) is effective on the activation of peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 value of 16.7 μM; however, saurufuran B (2), with an EC50 value of > 100 μM, weakly activated the PPARγ.

ISSN 

0163-3864

Link 

http://dx.doi.org/10.1021/np010440j

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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