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Title 

Inhibitory activity of plant extracts on matrix metalloproteinase-2

 

식물추출물의 matrix metalloproteinase-2에 대한 저해활성

Authors 

Sang Myung LeeHyo Kon ChunHo Jae LeeChoong Hwan LeeJin Hee KimYung Hee Kho

Publisher 

Korean Society of Pharmacognosy

Issue Date 

2002

Citation 

Korean Journal of Pharmacognosy, vol. 33, no. 2, pp. 137-143

Keywords 

matrix metalloproteinase-2youngia denticulateajuga decumbens extractaquilegia adoxoides extractbulpleurum longiradiatum extractcassiae tora extractcatalpa ovata extractcayratia japonica extractcephaldtaxus koreana extractchrysanthemum zawadskii extract

Abstract 

The inhibitory effects of methanol extracts of 165 medicinal herbs on matrix metalloproteinase-2 (MMP-2) activity were investigated. Amongst the herbal extracts, Youngia denticulate, Platycarya strobilacea, Sedum kamtschaticum, Euscaphis japonica, and Cornus controversa showed a significant inhibitory effect with above 80% at 1 μg/ml. Above mentioned five kind extracts, which exclude polyphenols and/or tannin by techniques for their removal, showed a mild inhibitory effect on MMP-2 activity except for Y. denticulate at the same concentration.

ISSN 

0253-3073

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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