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Title 

Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2tm1Lau mice with dermatitis

Authors 

Young Suk WonH J KwonGoo Taeg OhBang Hyun KimChul Ho LeeY H ParkByung Hwa HyunYang Kyu Choi

Publisher 

Wiley-Blackwell

Issue Date 

2002

Citation 

Microbiology and Immunology, vol. 46, no. 9, pp. 629-632

Keywords 

granulomatous dermatitisITS-PCRstaphylococcus xylosusbacterium identificationcoagulase negative Staphylococcusknockout mousemousedermatitismice

Abstract 

Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knock-out mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.

ISSN 

0385-5600

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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