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Title 

Benzastatin J, a new demethylated derivative of benzastatin B produced by controlled fermentation of Streptomyces nitrosporeus

Authors 

Won Gon KimIck Dong Yoo

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

2002

Citation 

Journal of Microbiology and Biotechnology, vol. 12, no. 5, pp. 838-840

Keywords 

benzastatindemethylationp-aminobenzoic acidstreptomyces nitrosporeussupplementation4 aminobenzamide4 aminobenzoic acidbenzamide derivativeglutamic acididebenone

Abstract 

Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Streptomyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.

ISSN 

1017-7825

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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