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Title 

Stilbenes from the roots of Pleuropterus ciliinervis and their antioxidant activities

Authors 

J P LeeByung Sun MinRen Bo AnM K NaSang Myung LeeHyeong Kyu LeeJ G KimK H BaeS S Kang

Publisher 

Elsevier

Issue Date 

2003

Citation 

Phytochemistry, vol. 64, no. 3, pp. 759-763

Keywords 

DPPH radical scavenging activitylipid peroxidation activitypieceid-2′-O-coumaratepieceid-2′-O-gallatepleuropterus ciliinervispolygonaceaesuperoxide radical scavenging activityantioxidantpleuropterus ciliinervis extractstilbene derivative

Abstract 

Two stilbene glycosides, pieceid-2″-O-gallate and pieceid-2″-O-coumarate, were isolated from the MeOH extract of the roots of Pleuropterus ciliinervis Nakai (Polygonaceae), together with two known compounds, resveratrol and pieceid. Their structures were determined spectroscopically, particularly by 2D NMR spectroscopic analysis. The antioxidant activities of stilbenes isolated were determined in vitro against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, superoxide radicals and by determining their lipid peroxidation inhibitory activities. Among the compounds isolated, pieceid-2″-O-gallate had the most potent inhibitory scavenging effect on DPPH, superoxide radicals and upon lipid peroxidation inhibition with IC50 values of 16.5, 23.9 and 5.1 μM, respectively.

ISSN 

0031-9422

Link 

http://dx.doi.org/10.1016/S0031-9422(03)00417-5

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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