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Title 

Lactones from the leaves of Litsea japonica and their anti-complement activity

Authors 

Byung Sun MinSun Young LeeJung Hee KimOk Kyoung KwonBo Young ParkRen Bo AnJoongku LeeHyung In MoonTae Jin KimY H KimHyouk JoungHyeong Kyu Lee

Publisher 

American Chemical Society

Issue Date 

2003

Citation 

Journal of Natural Products, vol. 66, no. 10, pp. 1388-1390

Keywords 

akolactonehamabiwalactone Ahamabiwalactone Blactonelitsealactone Alitsealactone Bcomplement activationcomplement inhibitionlitsea japonicaplant leaf

Abstract 

Two new lactones, litsealactone A (1) and litsealactone B (2), were isolated from the leaves of Litsea japonica, together with three known lactones, hamabiwalactone A (3), hamabiwalactone B (4), and akolactone B (5). Hamabiwalactone B (4) and akolactone B (5) significantly inhibited complement activity in an in vitro anti-complement assay, with IC50 values of 149 and 58 μM, respectively.

ISSN 

0163-3864

Link 

http://dx.doi.org/10.1021/np030227i

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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