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Title 

Synthesis of multi-substituted pyrazoles utilizing the N-alkylated 3-hydroxy-3-propargyl- or allenylisoindolines

Authors 

Y H ChoiKyung Soon KimSang Ku LeeTae Sook JeongH Y LeeY H KimWoo Song Lee

Publisher 

Elsevier

Issue Date 

2003

Citation 

Heterocycles, vol. 60, no. 11, pp. 2499-2510

Keywords 

3 hydroxy 3 propargylindolineallenylisoindolineindole derivativeunclassified drugalkylationcyclizationpolymerizationsynthesis

Abstract 

N-Alkyl-substituted phthalimides (1) were easily converted to di-, tri-, and tetra-substituted pyrazoles (10) via a one-pot addition-decyclization-cyclocondensation process. Then, the structure and the position of N1-substitution of the 1,3-pyrazole ring were determined by X-Ray crystallographic analysis and 1H-nOe experiments.

ISSN 

0385-5414

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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