상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Kaurane-type diterpene glycoside from the stem bark of Acanthopanax trifoliatus

Authors 

P V KiemX F CaiC V MinhJung Joon LeeY H Kim

Publisher 

Georg Thieme Verlag

Issue Date 

2004

Citation 

Planta Medica, vol. 70, no. 3, pp. 282-284

Keywords 

diterpeneplant glycosideacanthopanaxacanthopanax trifoliatusditerpenes, kauraneglycosidesplant barkeleutherococcus trifoliatus

Abstract 

A new diterpene glycoside, acantrifoside D (1), as well as three known diterpenes (2-4) were isolated from the stem bark of Acanthopanax trifoliatus from Vietnam. Based on 1D and 2D NMR spectroscopic data, their chemical structures were determined to be 16α,17-dihydroxy-ent-kauran-19-oic acid 16-O-β-D-glucopyranoside 19-O-β-D-glucopyranosyl ester (1), 16αH,17-isovalerate-ent-kauran-19-oic acid (2), ent-kaur-16-en-19-oic acid (3), and ent-pimara-8(14),15-dien-19-oic acid (4). Compounds 2-4 had strong inhibitory effects against COX-1 in an in vitro assay, with IC 50 values of 0.21, 0.15 and 0.19 mM, respectively.

ISSN 

0032-0943

Link 

http://dx.doi.org/10.1055/s-2004-818926

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)