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Title 

Quality evaluation of the cinnamon essential oils based on gas chromatographic analysis and cytotoxicity

 

가스 크로마토그래피 분석과 세포독성에 의한 계피 정유의 품질평가

Authors 

H J ParkH J JungW T JungJ ChoiJ H NamK T LeeByoung-Mog Kwon

Publisher 

Korean Society of Pharmacognosy

Issue Date 

2004

Citation 

Korean Journal of Pharmacognosy, vol. 35, no. 4, pp. 288-292

Keywords 

cinnamaldehydecinnamomumcytotoxicityGC-MShydroxycinnamaldehydequality evaluationcinnamon oilessential oilcinnamondrug cytotoxicity

Abstract 

To evaluate the quality of the crude drugs using three kinds of Cinnamomum Cortex (CC), Vietnamese CC (VCC, the stem bark of Cinnamomum obtusifolium), periderm-peeled Chinese CC (PPCC, periderm-peeled stem bark of C. cassia), Chinese CC (CCC, stem bark of C. cassia) and a Cinnamomi Ramulus (CR, the twig of C. cassia), the four essential oils were prepared by steam distillation method. Cinnamaldehdye (CNA) and an unknown substance tentatively named hydroxycinnamaldehdye (HCNA) were detected in the four essential oils by gas chromatography-mass spectrometry, the contents of which are significantly different one another. Vietnamese CC had the highest content of HCNA whereas CR had the highest CNA content and the lowest HCNA. Vietnamese CC exhibited the greatest cytotoxic activity against the cancer cell lines, A549, HepG-2, HL-60, P-388, U-937, and KB and CR the lowest cytotoxicity. Contents of CNA and HCNA in CCC and PPCC are positioned between VCC and CR. These results suggest that measurement of HCNA and cytotoxicity may determine the quality of CC and CR.

ISSN 

0253-3073

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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