상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

식용식물자원으로부터 활성물질의 탐색-XII: 꽃마리(Trigonotis peduncularis Benth.)로부터 Flavonol 배당체의 분리 및 hACAT1 저해활성

Authors 

H J YangM C SongM H BangJ H LeeI S ChungY H LeeTae Sook JeongByoung-Mog KwonS H KimD K KimM H ParkN I Baek

Publisher 

Korean Society for Applied Biological Chemisty

Issue Date 

2005

Citation 

Journal of Korean Society for Applied Biological Chemistry, vol. 48, no. 1, pp. 98-102

Keywords 

trigonotis peduncularisflavonol glycosideastragalinnicotiflorinrutinisoquercitrinhACAT1

Abstract 

The MeOH extracts obtained from whole plant of Trigonotis peduncularis Benth. were solvent fractionated using EtOAc, n-BuOH and water, successively. The EtOAc and n-BuOH fractions gave four flavonol glycosides through application of silica gel and octadecyl silica gel (ODS) column chromatographies. The chemical structures of the flavonol glycosides were determined by the interpretation of several spectral data including 2D-NMR as kaempferol-3-O-β-D-glucopyranoside (astragalin, 1), kaempferol-3-O-α-L-rhamnopyranosyl (1?6)-β-D-glucopyranoside (nicotiflorin, 2), quercetin-3-O-α-L-rhamnopyranosyl(1?6)-β-D-glucopyranoside (rutin, 3), quercetin-3-O-β-D-glucopyranoside (isoquercitrin, 4). The flavonoids have been first isolated from this plant. Nicotiflorin (100 μg/ml) showed 68.3?1.2% of the inhibitory effect on hACAT1(human Acyl CoA: cholesterol transferase 1) activity.

ISSN 

1738-2203

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)