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Title 

Inhibition of hepatitis B virus by an aqueous extract of Agrimonia eupatoria L.

Authors 

Dur Han KwonH Y KwonH J KimE J ChangM B KimS K YoonEun Young SongDo Young YoonY H LeeIn Seong ChoiYong Kyung Choe

Publisher 

Wiley-Blackwell

Issue Date 

2005

Citation 

Phytotherapy Research, vol. 19, no. 4, pp. 355-358

Keywords 

antiviral activityaqueous extractsgenus agrimoniaHBsAgseasonal variationagrimonia coreana pilosella extractagrimonia eupatoria extractagrimonia pilosa extracthepatitis B surface antigenplant extract

Abstract 

Inhibition of HBsAg release against hepatitis B virus (HBV) was investigated in an aqueous extract prepared from the aerial parts (stems and leaves) of Agrimonia eupatoria. The inhibitory effect on HBsAg secretion was footed using aqueous extracts of Agrimonia eupatoria at four different temperatures (37 °C 45 °C, 55 °C and 60 °C), and the extract prepared at 60 °C was found to have the greatest effect. The inhibitory activity of Agrimonia eupatoria extracts on HBsAg secretion varied over the growing season and was the highest at mid-July. This inhibitory activity was also shown with the aqueous extracts of two other species of the genus Agrimonia: A. pilosa and A. coreana pilosella. These results suggest that some plants of the genus Agrimonia contain potential antiviral activity against HBV.

ISSN 

0951-418X

Link 

http://dx.doi.org/10.1002/ptr.1689

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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