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Title 

Kitasatospora sp. MJM383 strain producing two antitumor agents, streptonigrin and oxopropaline G

Authors 

Y Y JinT M YoonWon Gon KimK R KimJ K SongJ G KimJ LiuY Y YangH J KwonJ W Suh

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

2005

Citation 

Journal of Microbiology and Biotechnology, vol. 15, no. 5, pp. 1140-1145

Keywords 

16S rDNA sequencekitasatospora sp. MJM383oxopropalinerare actinomycetestreptonigrinantineoplastic agentoxopropaline gunclassified drugbacterial straindrug structure

Abstract 

MJM383, a rare actinomycete sp. strain originated from Chinese soils, was isolated through an antimicrobial screening system. The analysis of 16S rDNA sequences and biochemical characterization determined the strain to belong to genus Kitasatospora. Both NMR and ESI mass data of its purified bioactive compounds revealed Kitasatospora sp. MJM383 to produce two antitumor agents, streptonigrin and oxopropaline G, which have been known to be produced from Streptomyces species. This is the first report to demonstrate the presence of antitumor agents produced by genus Kitasatospora.

ISSN 

1017-7825

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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