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Title 

A new variant of the mouse Akp1 locus

Authors 

Chul Ho LeeEun Hee KimYoung Suk WonY K ChoiKi Hoan NamHyoung-Chin KimByung Hwa HyunJ G SuhY S Oh

Publisher 

Springer Verlag (Germany)

Issue Date 

2005

Citation 

Biochemical Genetics, vol. 43, no. 11, pp. 597-602

Keywords 

alkaline phosphataseelectrophoresismus musculusalkaline phosphatase 1enzyme variantunclassified drugalleleanimal experimentanimal tissuefemale

Abstract 

A new electrophoretic migration type of alkaline phosphatase 1 (Akp1) was found on the cellulose acetate electrophoresis for kidney and liver homogenates of KWHM mouse, a newly established inbred strain derived from the Korean wild mouse (Mus musculus molossinus). This new type of alkaline phosphatase 1 was distinguished from previously reported AKP1A and AKP1B types in the mouse, and tentatively named AKP1C. In genetic analysis by mating experiments between KWHM and C57BL/6J (AKP1A) or BALB/cA (AKP1B), the phenotypic segregation ratios of AKP1A : AKP1AC : AKP1C or AKP1B : AKP1BC : AKP1C were 1 : 2 : 1 in both groups of F2 generations. It was therefore concluded that AKP1C type is controlled by Akp1c allele which is codominant with Akp1a and Akp1 b alleles.

ISSN 

0006-2928

Link 

http://dx.doi.org/10.1007/s10528-005-9116-5

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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