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Title 

Proteomic analysis of pathogenic bacterium Vibrio vulnificus

Authors 

Ah Young LeeSung Goo ParkMi JangS ChoP K MyungY R KimJ H RheeDo Hee LeeByoung Chul Park

Publisher 

Wiley-Blackwell

Issue Date 

2006

Citation 

Proteomics, vol. 6, no. 4, pp. 1283-1289

Keywords 

2-DEToxRvibrio vulnificusvirulencebacterial virulenceprotein analysisproteomicsbacterial proteinsbacteria (microorganisms)

Abstract 

In this study we have constructed a proteome reference map of the pathogenic bacterium Vibrio vulnificus. From the reference map, we identified several virulence-related proteins, such as ToxR and ToxS, as well as numerous proteins involved in diverse cellular functions. To search for additional virulence-related proteins, we compared the whole proteomes from the wild-type and toxR mutant of V. vulnificus and found that several proteins were up- or down-regulated in the toxR mutant. We suggest that these differentially regulated proteins whose expression is coordinately controlled by a virulence regulator ToxR, some of which are already implicated in virulence, play roles in the pathogenesis of V. vulnificus.

ISSN 

1615-9853

Link 

http://dx.doi.org/10.1002/pmic.200500393

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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