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Title 

Analysis of DNA methylation profiles in preimplantation embryos using bisulfite mutagenesis

Authors 

Yong Mahn HanS H KimYong-Kook Kang

Publisher 

Humana Press

Issue Date 

2005

Citation 

Methods in Molecular Biology, vol. 325, no. 0, pp. 251-260

Keywords 

primer DNADNA methylationmutagenesisDNA primersDNA restriction enzymes

Abstract 

For developmental competence of mammalian embryos, dynamic epigenetic changes to both the maternally and paternally derived contributions to the genome of the zygote should be brought about in the early cleavage stages. DNA methylation is a typical epigenetic mark modified during pre-implantation development. Here, we describe how to analyze DNA methylation profiles in early-stage embryos.

ISSN 

1064-3745

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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