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Title 

Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3)

 

바이플라보노이드의 PRL-3 저해활성

Authors 

Sung-Kyu ChoiH M OhSu-Kyung LeeDae Gwin JeongSeong Eon RyuKwang Hee SonDong Cho HanN D SungN I BaekByoung-Mog Kwon

Publisher 

Taylor & Francis

Issue Date 

2006

Citation 

Natural Product Research, vol. 20, no. 4, pp. 341-346

Keywords 

biflavonoidsginkgetinmetastasisPRL-3sciadopitysintaxus cuspidataphosphataseliver regenerationprotein-tyrosine-phosphatase

Abstract 

Two biflavonoids, ginkgetin (1) and sciadopitysin (2), were isolated from the MeOH extract of the young branches of Taxus cuspidata, which inhibited phosphatase of regenerating liver-3 (PRL-3) with IC50 values of 25.8 and 46.2 μM, respectively. This is the first report on PRL-3 inhibitors, isolated from natural sources.

ISSN 

1478-6419

Link 

http://dx.doi.org/10.1080/14786410500463312

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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