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Title 

Synthesis and cytotoxic activities of 8-alkyl or 8-aryl-8,9-dihydro-7H-isoindolo[5,6-g]quinoxaline-7,9-diones

Authors 

J K JungE K JungK Nam-GoongJ S ChoHwan Mook KimSong Kyu ParkYeong-Ah YooJoo-Hee KwonH S Lee

Publisher 

Pharmaceutical Society of Korea

Issue Date 

2006

Citation 

Archives of Pharmacal Research, vol. 29, no. 4, pp. 276-281

Keywords 

cytotoxic activityisoindoloquinoxalinesynthesis

Abstract 

A series of 8-alkyl- and 8-aryl-8,9-dihydro-7H-isoindolo[5,6- g]quinoxaline-7,9-diones were synthesized using sultine chemistry as a key step in good yield. These compounds were evaluated for their in vitro cytotoxicity against six human cancer cell lines (HCT15, SK-OV-3, A549, SNB19, MCF7 and MCF7/ADR).

ISSN 

0253-6269

Link 

http://dx.doi.org/10.1007/BF02968570

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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