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Title 

Two novel furan derivatives from Phellinus linteus with anti-complement activity

 

항보체효과를 갖는 상황버섯의 퓨란화합물

Authors 

B S MinBong Sik YunHyeong Kyu LeeH J JungH A JungJ S Choi

Publisher 

Elsevier

Issue Date 

2006

Citation 

Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 12, pp. 3255-3257

Keywords 

anti-complement activityfuran derivativesphellinus linteusstructural determinationerythrocyte antibodyfuran derivativephellinusfuran aphellinusfuran bcomplement inhibition

Abstract 

Two novel stereoisomers of furan derivatives, phellinusfurans A (1) and B (2), were isolated from the fruiting body of Phellinus linteus. Their structures were elucidated by spectroscopic analysis. Compounds 1 and 2 exhibited significant anti-complement activity with IC50 values of 33.6 and 33.7 μM, respectively, in inhibiting the hemolytic activity of human serum against erythrocytes.

ISSN 

0960-894X

Link 

http://dx.doi.org/10.1016/j.bmcl.2006.03.027

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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