상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Antioxidant activities of abietane diterpenoids isolated from Torreya nucifera leaves

Authors 

Woo Song LeeJ R KimJong Min HanK C JangD E SokTae Sook Jeong

Publisher 

American Chemical Society

Issue Date 

2006

Citation 

Journal of Agricultural and Food Chemistry, vol. 54, no. 15, pp. 5369-5374

Keywords 

abietane diterpenoidsantioxidant activityatherosclerosisINOSLDLNOtorreya nuciferaabietane derivativeantioxidantplant leaf

Abstract 

Investigation on antioxidant compounds from the ethanolic extracts of Torreya nucifera leaves resulted in the isolation of abietane diterpenoids, a known 18-methylesterferruginol (1) and a new 18-dimethoxyferruginol (2). The structures of compounds 1 and 2 were elucidated on the basis of their spectroscopic analyses. Compounds 1 and 2 inhibited the Cu2+- mediated, 2,2′-azobis(2-amidino-propane)hydrochloride-mediated and 3-morpholinosydnonimine-1-mediated low-density lipoprotein (LDL) oxidation in the thiobarbituric acid-reactive substances assay as well as the macrophage-mediated LDL oxidation. Compounds 1 and 2 exhibited the potent antioxidant activities in the conjugated diene production, relative electrophoretic mobility, and apoB-100 fragmentation on copper-mediated LDL oxidation. Compound 1 also suppressed nitric oxide production and inducible nitric oxide synthase expression in lipopolysaccharide-stimulated RAW264.7 cells.

ISSN 

0021-8561

Link 

http://dx.doi.org/10.1021/jf060896c

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)