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Title 

Talosins A and B: new isoflavonol glycosides with potent antifungal activity from Kitasatospora kifunensis MJM341: 2. physicochemical properties and structure determination

Authors 

Won Gon KimT M YoonH J KwonJ W Suh

Publisher 

Nature Publishing Group

Issue Date 

2006

Citation 

Journal of Antibiotics, vol. 59, no. 10, pp. 640-645

Keywords 

6-deoxy-taloseantifungal agentgenisteinisoflavonol glycosidekitasatospora kifunensistalosin Atalosin Bglycosideantifungal activity

Abstract 

In our screening program for new antifungal agents from microbial secondary metabolites, two new isoflavonol glycosides with potent antifungal activity, talosins A and B, were isolated from the culture broth of Kitasatospora kifunensis MJM341. Talosins A and B were determined to be genistein 7-α-L-6-deoxy-talopyranoside and genistein 4′,7-di-α-L-6- deoxy-talopyranoside, respectively, by spectroscopic studies. They are the first flavonoid glycosides incorporating 6-deoxy-talose as a sugar component.

ISSN 

0021-8820

Link 

http://dx.doi.org/10.1038/ja.2006.85

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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