상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Antimicrobial activity of N-acetyl-phenylalanine produced from Streptomyces sp. G91353

 

Streptomyces sp. G91353이 생산하는 N-acetyl-phenylalanine의 항균활성

Authors 

Oh-Sung KwonH R ParkBong Sik YunJ H HwangJae-Chan LeeDong Jin parkChang-Jin Kim

Publisher 

The Korean Society for Applied Microbiology and Biotechnology

Issue Date 

2006

Citation 

Korean Journal of Microbiology & Biotechnology, vol. 34, no. 4, pp. 306-310

Keywords 

actinomycetesantimicrobial activityD-alanyl-D-alanineMICN-acetyl-phenylalanineamino acid derivativedextro alanyl dextro alaninen acetylphenylalanineactinobacteriabacterial strain

Abstract 

For screening of the compounds exhibiting antimicrobial activities against the D-alanyl-D-alanine of Gram positive bacteria, approximately 2,500 actinomycetes isolated from soil were examined for antimicrobial activity. In consequence, we recently isolated the Streptomyces sp. G91353 strain produced an active compound, A91353, that inhibits the growth of Gram positive bacteria. A91353 was identified as N-acetyl-phenylalanine by various spectroscopic methods. The minimum inhibitory concentration (MIC) values of N-acetyl-phenylalanine on Gram positive bacteria such as Streptococcus pyogenes 308A, Streptococcus pyogenes 77A were determined as 50 μg/ml, respectively, but did not effect on Gram negative strains. These results indicate that N-acetyl-phenylalanine have an antimicrobial activity, which may be caused by the disturbance of D-alanyl-D-alanine synthesis.

ISSN 

0257-2389

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)