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Title 

Anti-proliferation effects of isorhamnetin isolated from Persicaria thunbergii on cancer cell lines

Authors 

Byoung-Mog Kwon

Publisher 

Korean Society of Pharmacognosy

Issue Date 

2006

Citation 

Natural Products Sciences, vol. 12, no. 4, pp. 214-216

Keywords 

anti-proliferative activityisorhamnetinpersicaria thunbergiianimal cellantineoplastic activitycancer cell culturecancer growthcell proliferationdrug effecthuman cell

Abstract 

Isorhamnetin from the aerial parts of Persicaria thunbergii has been reported to have anti-tumor activity mediated by the inhibition of farnesyl protein transferase. In this study, we investigated the antiproliferation effects of isorhamnetin on NIH3T3, K-RAS, H-RAS and SW620 cells, and it showed antiproliferative effects in a dose-dependent manner with IC50 value 4.1, 7.9, 20.2, and 22.4 μg/ml, repectively.

ISSN 

1226-3907

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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