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Title 

Verticillin G, a new antibacterial compound from Bionectra byssicola

Authors 

C H ZhengS H ParkH KoshinoY H KimWon Gon Kim

Publisher 

Nature Publishing Group

Issue Date 

2007

Citation 

Journal of Antibiotics, vol. 60, no. 1, pp. 61-64

Keywords 

anti-MRSAbionectra byssicolaepidithiodioxopiperazineverticillin Gantiinfective agentpiperazine derivativechemical structuredrug effectfungus

Abstract 

A new epidithiodioxopiperazine compound named verticillin G along with the known compound verticillin D has been isolated from the mycelium of liquid fermentation cultures of a fungal strain Bionectra byssicola F120. The structure of verticillin G was determined on the basis of MS and NMR data. Verticillin G inhibited the growth of Staphylococcus aureus including methicillin-resistant and quinolone-resistant S. aureus with MIC (μg/ml) of 3-10.

ISSN 

0021-8820

Link 

http://dx.doi.org/10.1038/ja.2007.8

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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