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Title 

Isolation of constituents and anti-complement activity from Acer okamotoanum

Authors 

W Y JinB S MinJ P LeeP T ThuongHyeong Kyu LeeK S SongY H SeongK H Bae

Publisher 

Pharmaceutical Society of Korea

Issue Date 

2007

Citation 

Archives of Pharmacal Research, vol. 30, no. 2, pp. 172-176

Keywords 

β-Sitosterol glucoside-3′-O-hexacosanoicateacer okamotoanumaceraceaeacylated sterol glucosideanti-complement activitycomplement inhibitoracercomplement classical pathwayisolation and purificationstructure activity relation

Abstract 

A novel acylated sterol glucoside (1) along with four known compounds, β-amyrin acetate (2), 3β,24-dihydroxytaraxer-14-ene (3), cleomiscosin A (4), and cleomiscosin C (5), were isolated from the leaf and twig of Acer okamotoanum Nakai (Aceraceae). The structure of the new compound was determined to be β-sitosterol glucoside-3′-O-hexacosanoicate based on chemical and spectroscopic analyses. In addition, the novel compound was found to exhibit a significant inhibitory effect (IC50 value of 0.2 μM) on the complement system activated by the classical pathway.

ISSN 

0253-6269

Link 

http://dx.doi.org/10.1007/BF02977691

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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