상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Glioperazine B, as a new antimicrobial agent against Staphylococcus aureus, and glioperazine C: two new dioxopiperazines from Bionectra byssicola

Authors 

C J ZhengY H KimWon Gon Kim

Publisher 

Japan Society for Bioscience, Biotechnology and Agrochemistry

Issue Date 

2007

Citation 

Bioscience Biotechnology and Biochemistry, vol. 71, no. 8, pp. 1979-1983

Keywords 

antibacterialbionectra byssicoladioxopiperazinestaphylococcus aureusamino acidsfermentationmetabolitesnuclear magnetic resonance spectroscopyantibacterial activity

Abstract 

In the course of our screening for new antibacterials from microbial metabolites, two new dioxopiperazine metabolites, glioperazines B (1) and C (2), together with the known compound, glioperazine (3), were isolated from the mycelia of a liquid fermentation culture of the fungus, Bionectra byssicola F120. The structures of compounds 1 and 2 were assigned on the basis of MS and NMR data. Compound 1 is an unusual dioxopiperazine metabolite containing an OMe group at the α-carbon of the amino acid residue. Compound 1 showed weak antibacterial activity against various strains of S. aureus, including methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), while 2 and 3 did not show such activity.

ISSN 

0916-8451

Link 

http://dx.doi.org/10.1271/bbb.70167

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)