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Title 

New antioxidant polyphenols from the medicinal mushroom Inonotus obliquus

Authors 

In Kyoung LeeYoung Sook KimYun Woo JangJ Y JungBong Sik Yun

Publisher 

Elsevier

Issue Date 

2007

Citation 

Bioorganic & Medicinal Chemistry Letters, vol. 17, no. 24, pp. 6678-6681

Keywords 

free radical scavengerhispidin derivativeinonoblinsinonotus obliquusmushroomantioxidantinonotus obliquus extractpolyphenol derivativeantioxidant activityplants, medicinal

Abstract 

The fruiting body of Inonotus obliquus, a medicinal mushroom called chaga, has been used as a traditional medicine for cancer treatment. Although this mushroom has been known to exhibit potent antioxidant activity, the mechanisms responsible for this activity remain unknown. In our investigation for free radical scavengers from the methanolic extract of this mushroom, inonoblins A (1), B (2), and C (3) were isolated along with the known compounds, phelligridins D (4), E (5), and G (6). Their structures were established by extensive spectroscopic analyses. These compounds exhibited significant scavenging activity against the ABTS radical cation and DPPH radical, and showed moderate activity against the superoxide radical anion.

ISSN 

0960-894X

Link 

http://dx.doi.org/10.1016/j.bmcl.2007.10.072

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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