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Title 

Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha

Authors 

Yun Woo JangIn Kyoung LeeYoung Sook KimSangku LeeHo Jae LeeS H YuBong Sik Yun

Publisher 

Nature Publishing Group

Issue Date 

2007

Citation 

Journal of Antibiotics, vol. 60, no. 11, pp. 696-699

Keywords 

antifungal activitymushroompolypropionatexylaria polymorphaxylarinic acid2,4,6 trimethyl 2 octenoic acid4,6,8 trimethyl 2,4 decadienoic acidantifungal agentmonounsaturated fatty acidtetrazolium

Abstract 

Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.

ISSN 

0021-8820

Link 

http://dx.doi.org/10.1038/ja.2007.89

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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