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Title 

Development of biologically active compounds from edible plant sources-XXIV : Anti-cancer activity of alcohol extracts from edible plants

 

식용 식물 추출물의 항암 활성

Authors 

H Y KwakByoung-Mog KwonM C SongJ H LeeH J YangD K KimE M AhnN I Baek

Publisher 

Korean Society of Pharmacognosy

Issue Date 

2007

Citation 

Korean Journal of Pharmacognosy, vol. 38, no. 4, pp. 312-320

Keywords 

edible plantanti-cancerFPTaseSTAT3PRL-3

Abstract 

The screening of anti-cancer activity for the MeOH extracts of 163 natural sources, which were registered as edible plants by Korea Food & Drug Administration, exhibited 9 extracts to have significant inhibitory effects on farnesyl-protein transferase (FPTase) and phosphatase of regenerating liver-3 (PRL-3). In order to confirm the inhibitory activity of these active extracts, the activity assay was repeated for some fractions obtained from the active extracts using Medium Pressure Liquid Chromatography (MPLC). Some fractions of Carya illinoensis, Chlorella vulgaris, Panicum miliaceum, Perilla frutescens, Rosmarinus officinalis showed over 50% inhibitory activity on FPTase as well as those of Capsella bursa-pastoris, C. illinoensis, C. vulgaris, Coix lacrymajobi, Myristica fragrans, P. miliaceum, R. officinalis did over 50% inhibitory activity on PRL-3.

ISSN 

0253-3073

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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