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Title 

Gene-set approach for expression pattern analysis

 

유전자 발현 패턴 분석을 위한 유전자 세트 분석 방법

Authors 

Dougu NamSeon-Young Kim

Publisher 

Oxford University Press (OUP)

Issue Date 

2008

Citation 

Briefings in Bioinformatics, vol. 9, no. 3, pp. 189-197

Keywords 

differential expression of genesDNA microarraygene set analysisgene expressiongene expression profilinggenetic analysisgenetic databasequantitative analysisstatistical analysisoligonucleotide array sequence analysis

Abstract 

Recently developed gene set analysis methods evaluate differential expression patterns of gene groups instead of those of individual genes. This approach especially targets gene groups whose constituents show subtle but coordinated expression changes, which might not be detected by the usual individual gene analysis. The approach has been quite successful in deriving new information from expression data, and a number of methods and tools have been developed intensively in recent years. We review those methods and currently available tools, classify them according to the statistical methods employed, and discuss their pros and cons. We also discuss several interesting extensions to the methods.

ISSN 

1467-5463

Link 

http://dx.doi.org/10.1093/bib/bbn001

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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