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Title 

Multifunctional silica nanocapsule with a single surface hole

Authors 

Yong Taik LimJ K KimYoung Woock NohMi Young JoBong Hyun Chung

Publisher 

Wiley-Blackwell

Issue Date 

2009

Citation 

Small, vol. 5, no. 3, pp. 324-328

Keywords 

imaginglabelingmagnetic materialsnanoparticlessilicaammonium compoundsfunctional polymersmagnetic devicesmagnetic fields

Abstract 

The fabrication of multifunctional silica nanocapsules containing magnetic nanoparticles and fluorescent quantum dots (QD) was reported, and the dual mode imaging properties of the nanocapsules were also examined. The nanocapules were internalized by phagocytic dendritic cells and were found to be potent bimodal imaging contrast agents. The surfactant cetyltrimethylammonium bromide (CTAB) solution added to the organic solutions containing QDs and magnetic NPs is found to stabilize organic droplets in the water phase. Scanning electron microscopy (SEM) images show that the silica nanocapsules have only a single hole on each surface. A magnetic field applied to the aqueous dispersions of silica nanocapsules shows that the nanocapsules are easily collected, suggesting the presence of magnetic nanoparticles in nanocapsules. Single surface hole silica nanocapsule is found to be easily encapsulated by a polymer coating after loading therapeutic drugs.

ISSN 

1613-6810

Link 

http://dx.doi.org/10.1002/smll.200800935

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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