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Title 

A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6

 

이중선택성 탈인산화효소 MKP-6에 선택적인 형광 ESIPT 탐침 개발

Authors 

T I KimHyo Jin KangG HanSang Jeon ChungY Kim

Publisher 

Royal Society of Chemistry

Issue Date 

2009

Citation 

Chemical Communications, vol. 2009, no. 39, pp. 5895-5897

Abstract 

A highly selective fluorescent probe for a protein tyrosine phosphatase (PTP) was designed by a simple phosphorylation of the 2-(2′-hydroxyphenyl) benzothiazole (HBT) chromophore: upon selective enzymatic hydrolysis, an excited-state intramolecular proton transfer (ESIPT) occurs, resulting in a large Stokes shift.

ISSN 

1359-7345

Link 

http://dx.doi.org/10.1039/b911145j

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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