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Title 

Phytochemical mediated gold nanoparticles and their PTP 1B inhibitory activity

Authors 

S K BashaK GovindarajuR ManikandanJong Seog AhnEun Young BaeG Singaravelu

Publisher 

Elsevier

Issue Date 

2010

Citation 

Colloids and Surfaces B-Biointerfaces, vol. 75, no. 2, pp. 405-409

Keywords 

Biological synthesisGold nanoparticlesGuavanoic acidPTP 1B

Abstract 

Current discovery demonstrates the rapid formation of gold nanoparticles with guavanoic acid a phytochemical of Psidium guajava (Pg). The pharmacological capabilities of the phytochemicals present in the leaves of Pg and their ability to generate gold nanoparticles is presented herein. The new genre of green nanoparticles exhibit remarkable Protein Tyrosine Phosphatase 1B (PTP 1B) inhibitory activity and in vitro stability in various physiological medium including saline, histidine, cysteine, bovine serum albumin (BSA), human serum albumin (HSA) and buffers (pH 5, 7 and 9). It is predicted that this new technology will be felt greatly in several routes of pharmaceuticals.

ISSN 

0927-7765

Link 

http://dx.doi.org/10.1016/j.colsurfb.2009.09.008

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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